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Subpages:
Syphilis 1938
EstenosisPilóricas
Pyloric Stenosis
Donatian Therapy 1976
Uruguay 2003

   

 

Up ] [ Articles ] Documents ] Patents ] Bibliography ]


| General Scientific | Cancer | Historical  | Breast Cancer | HIV/AIDS |
| Brain & Central Nervous System | Cardiovascular & Vascular | Ulcers |
| Syphilis & other Infectious Diseases | Other Non-diabetic Uses of Insulin |
| Oncodiagnosticator | Other Articles |

More articles will be added as they come in, as they surface in the archives, and as  time permits.   Where possible, permission has been obtained from the copyright holders.   Copyrighted material will be removed at copyright holder's request.   Some older articles have historic value and may not reflect the latest IPT information and theories.

General Scientific Articles

Insulin potentiation therapy: a new concept for management of chronic degenerative disease   (SGA,  D. Perez Garcia y Bellon and D. Perez Garcia, Jr., Medical Hypotheses 20(2):199-210, 1986)

The Physiology and Clinical Pharmacology of Insulin in Relation to its Application in Insulin Potentiation Therapy  (SGA, M.D.   Unpublished article, 1990.)
[summary by C Duffield]

Cancer

Insulin-induced enhancement of antitumoral response to methotrexate in breast cancer patients.  Lasalvia-Prisco E, Cucchi S, Vazquez J, Lasalvia-Galante E, Golomar W, Gordon W.   Cancer Chemotherapy and Pharmacology. 2003 Dec 4 [Epub ahead of print]. 
The very first publication of IPT clinical trial data.  IPT very significantly improved clinical outcome of low dose chemotherapy in patients with advanced breast cancer.

The effect of insulin on chemotherapeutic drug sensitivity in human esophageal and lung cancer cells.   Jiao SC, Huang J, Sun Y, Lu SX.  Zhonghua Yi Xue Za Zhi. 2003 Feb 10;83(3):195-7. [article in Chinese]
Insulin significantly enhanced the killing effect of three chemotherapy drugs on esophageal and lung cancer cell lines.

Insulin, Chemotherapy, and the Mechanisms of Malignancy: the design and the demise of cancer   SGA, D.P. Garcia y Bellon, D.P. Garcia Jr, Medical Hypotheses (2000) 55(4) 330-334, 2000.

Hoist by One's Own Petard:  The design and the demise of cancer (SGA, M.D., Townsend Letter for Doctors and Patients, October 1999, pages 94-96.)  [URL to page on Dr. SGA's website]

Insulin and cancer chemotherapy (SGA, M.D., unpublished article, 1987  [summary by C Duffield]

Metabolic Modification by Insulin Enhances Methotrexate Cytotoxicity in MCF-7 Human Breast Cancer Cells  Alabaster O, Vonderhaar BK, and Shafie SM, 1981, European Journal of Cancer and Clinical Oncology 17(11):1223-1228.  [pdf file, requires Adobe Reader] 

 

General Public Articles

Historical Articles

The Medicine You Never Knew  (Chris Duffield PhD, op ed article submitted to the New York Times, December 8, 2000.

The History of Insulin Potentiation Therapy   (SGA, M.D., unpublished article, 1997) [URL to page on Dr. SGA's website]

 Cellular Therapy to Change the Biophysical-Biochemical Constants of the Blood, or Donatian Therapy, Drs. Donato Perez Garcia (SGA MD, 1976, self-published report, 41 pages).  Based on his visit to Dr. Perez Garcia 2.

Biological, Biochemical, and Physicochemical Mechanisms of Insulin that Take Part in Donatian Therapy for Treating Cancer  (Mechanismos Biologicos, Bioquimicos y Fisico-Quimicos de la Insulina que Intervienen en la Terapeutica Donatiana para la Curacion de los Enfermos de Cancer), by Donato Perez Garcia y Bellon.  (Year unknown, unpublished paper.)  84 pages.
Full Text (PDF) of original in Spanish  (requires Adobe Reader)

Insulin for Everything  (Time Magazine   April 10, 1944, pages 43-44   -- article about Donato 1.)

Curing Mental and Nervous System Illnesses, a Mexican doctor talks about his experiments in the United States  (Enrique Ortega, La Prensa (newspaper), San Antonio, Texas, 19 June 1938, translated from Spanish)

Breast cancer

Insulin-induced enhancement of antitumoral response to methotrexate in breast cancer patients.  Lasalvia-Prisco E, Cucchi S, Vazquez J, Lasalvia-Galante E, Golomar W, Gordon W.   Cancer Chemother Pharmacol. 2003 Dec 4 [Epub ahead of print]. 
The very first publication of IPT clinical trial data.

Primary breast conserving treatment for breast cancer using biologic response modification with insulin in combination with non-toxic low-dose chemotherapy.  SGA.  Poster presentation at the Third Annual Comprehensive Cancer Management Conference,  Washington DC, June, 2000.  [URL to page on Dr. SGA's website]

Breast preserving treatment for newly diagnosed breast cancer (SGA, M.D., unpublished article, April 1999)
[summary by C Duffield, and URL to page on Dr. SGA's website]

An outlook on breast cancer management   (SGA, M.D., unpublished article, 1999)  [summary by C Duffield]

Insulin shows promise as BRM in breast cancer regimens.  (Oncology News, 1991, 17(4):1,7.)

Insulin Plus Low-Dose CMF as Neo-Adjuvant Chemohormonal Therapy for Breast Carcinoma. SGA, M.D., Donato Perez Garcia y Bellon, M.D., Donato Perez Garcia, Jr., M.D.    The Third International Congress on Neo-adjuvant Chemotherapy, Paris, France, February 6-9, 1991.  

Neoadjuvant low-dose chemotherapy with insulin in breast carcinomas (SGA, Donato Perez Garcia y Bellon, Donato Perez Garcia Jr., 1990,  European Journal of Cancer 26(11-12):1262-3.)

Breast carcinoma treated by a regimen of low-dose chemotherapy and insulin:  report of four cases and pharmacokinetic considerations  (SGA, Donato Perez Garcia y Bellon, Donato Perez Garcia Jr., poster abstract at 42nd Annual Symposium on Fundamental Cancer Research, Cellular and Molecular Targets of Cancer Therapy, M.D.Anderson Cancer Center, University of Texas, Houston, Texas, October 24-27, 1989)  

AIDS/HIV

New Approaches to the Delivery of Drugs to the BrainSGA  Medical Hypotheses 29:283-291, 1989.  [URL to page on Dr. SGA's website]

Blood-brain barrier passage of azidothymidine in rats:  effects of insulin.  SGA, Brian Skaletski, and Aron D. Mosnaim.  Res Commun Chem Pathol Pharmacol. 1989 Jan;63(1):45-52.  [URL to page on Dr. SGA's website]

Insulin potentiation therapy and the auto-reinfection hypothesis of HIV-related disease.   SGA, unpublished paper.  1987. Poster presentation(?)  [Summary by C Duffield] 

Insulin potentiation therapy and the treatment of the acquired immunodeficiency syndrome.  SGA, M.D., unpublished article, 1987.  Poster presentation(?)   [Summary by C Duffield]

IPT and the treatment of HIV infection:  clinical experience to date.  SGA, M.D., Donato Perez Garcia y Bellon, M.D., Donato Perez Garcia, Jr., M.D.   Unpublished article, 1987.  Poster presentation.

Brain & Central Nervous System (CNS)

New Approaches to the Delivery of Drugs to the BrainSGA,  Medical Hypotheses 29:283-291, 1989  [URL to page on Dr. SGA's website]

Blood-brain barrier passage of azidothymidine in rats:  effects of insulin.  SGA, Brian Skaletski, and Aron D. Mosnaim.  Res Commun Chem Pathol Pharmacol. 1989 Jan;63(1):45-52.  [URL to page on Dr. SGA's website]

The entry of [D-penicillamine2,5]enkephalin into the central nervous system: saturation kinetics and specificity.  Thomas SA, Abbruscato TJ, Hruby VJ, Davis TP.  J Pharmacol Exp Ther. 1997 Mar;280(3):1235-40.

Insulin enhancement of opioid peptide transport across the blood-brain barrier and assessment of analgesic effect.  Witt KA, Huber JD, Egleton RD, Davis TP.  J Pharmacol Exp Ther. 2000 Dec;295(3):972-8.

Cardiovascular and Vascular

Glucose-Insulin-Potassium for Acute Myocardial Infarction -- Remarkable Results From a New Prospective, Randomized Trial [editorial] by Carl S. Apstein, MD.  Circulation. 1998 98(21):2223-2226.

Metabolic Modulation of Acute Myocardial Infarction -- The ECLA Glucose-Insulin-Potassium Pilot Trial  by Rafael Díaz; Ernesto A. Paolasso, et al.  Circulation. 1998 98(21):2227-2234. Abstract

GIK therapy is controversial and not fully proven.  More articles.

Ulcers

Some cases of pyloric stenosis cured without surgical intervention   [English translation]. 
Algunas estenosis pilóricas curadas sin intervención quirúrgica
[Original Spanish/Español version]
.
  Donato Perez Garcia [1], paper presented to the Ninth National Assembly of Surgeons, Mexico City, November 1950.  19 pages. This is an earlier version of part of chapter 3 of his 1953 book "Cellular Therapy".

The treatment of gastro-duodenal ulcers with Cellular Therapy 
(El tratamiento de las ulceras gastro-duodenales por la Terapeutica Celular), paper presented by Dr. Donato Perez Garcia at the Tercer Congreso Mexicano de Medicina, November 7-13, 1948, presented November 12. [We do not have a copy of this paper, but would like to.  Most likely it was very similar to the first half of the chapter on Peptic Ulcer in his book "Cellular Therapy".]


Syphilis and other infectious diseases

Cellular permeability as a basis for radical treatment of syphilis:  treatment of neurosyphilis and syphilis with insulin.  (La permeabilidad celular como base en el tratamiento radical de la sífilis: tratamiento de la neuro-sífilis y de la sífilis por la insulina)      by Dr. Donato Perez Garcia, Revista Medica Militar, vol. 1, no. 2, May-June 1938, pages 1-77.
Full text (PDF)  (requires Adobe Reader)

Treatment of typhus exanthematicus by cellular therapy by means of the change of the blood constants (El tratamiento del tifo exantematico con la Terapeútca Celular por el Cambio de las Constantes Sanguineas), paper presented by Dr. Donato Perez Garcia [1] at the Congreso del Tifo, October 1945, Mexico.  [We would like to get a copy of this...]

Other non-diabetic uses of insulin

UC Riverside Research Team Discovers that Insulin Heals Wounds
Press Release, January 5, 2007  (Article in press)

Non-diabetic uses for insulin Hal A. Huggins, D.D.S.  Journal of the International Academy of Preventive Medicine (IAPM) July 1977

Bodybuilding and the insulin enigma  (VirtualMuscle.com)
                Archived copy on this website

Oncodiagnosticador

The Oncodiagnosticator, Physical and Chemical Fundamentals.  Donato Perez Garcia y Bellon, unpublished paper, 1980s (?)  Available exclusively on IPTQ.org.

Quantitative determination of 18 mineral elements in blood serum: values in chronic-degenerative diseases, previously diagnosticated.   Unpublished paper, Donato Perez Garcia, 1984.  Available exclusively on IPTQ.org.

Other Related Articles

A new germ theory.  [link]  by Judith Hooper, article published in The Atlantic Monthly, February, 1999.

The value of IPT  by Chris Duffield, unpublished article originally appeared on IPTQ.org [PDF format requires Adobe Acrobat 4.0 or higher].

Socialization of medicine in Mexico with a medical technique invented in Mexico:  Cellular Therapy by Changing the Properties of the Blood (La socialización de la medicina en México con una tecnica medica inventada en México -- Terapeútica Celular por el Cambio de las Constantes Sanguineas), by Augustin Agagon Leiva and Donato Perez Garcia, Tte.Cor.M.C., a study and project presented to the II Congreso Mexicano de Ciencias Sociales, Mexico DF, October 12-31, 1945. (printed by Editorial Chililico).

Subpages:  Syphilis 1938 ] EstenosisPilóricas ] Pyloric Stenosis ] Donatian Therapy 1976 ] Uruguay 2003 ]

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